Ketogenic diet kd therapy is an established form of treatment for both pediatric and adult patients with intractable epilepsy. The role for ketogenic diets in epilepsy and status. It is a high fat, adequate protein, low carbohydrate diet. Most people who have seizures, also known as epilepsy, take medicine to prevent seizures.
In metabolic conditions, cancer, trauma, and ischemia, the ketogenic diet may confer a protective effect by providing an additional energy substrate to tissue at risk of cell death. Indications and contraindications of the ketogenic diet. Thirtyseven patients with essential or idiopathic epilepsy, whose parents were able to comprehend and carry out the diet intelligently at home, have been. The cochrane library of clinical trials was searched using the term ketogenic diet. Nature of the ketogenic diet the existence of the kd dates back to old times. Medline searches were performed using the keywords epilepsy therapy, dietary therapy, and epilepsy, and the text word ketogenic diet. Ketogenic diets in the treatment of epilepsy drug and. Persistent ketosis was possible in adults, and the diet was tolerable for most patients. Wilder, md, at mayo clinic, 1,3 hippocrates established in the. Ketogenic diet epilepsy action australiaepilepsy action. In fact, the ketogenic diet, like taking medications or having surgery, is a serious medical treatment. It is essentially a strict diet high in fats and low in carbohydrates. The gut microbiota mediates the antiseizure effects of the.
The ketogenic diet kd was found to be effective in treatment of intractable seizures. The ketogenic diet kd is a highfat, lowcarbohydrate diet with adequate protein thats a. The classic ketogenic diet is a special highfat, lowcarbohydrate diet that helps to control seizures in some people with epilepsy. Ketogenic diet therapy for epilepsy johns hopkins hospital. Although studies demonstrate kds success in reducing seizures stretching back nearly a century, the last 25 years have seen a resurgence in diet therapy for the management of drugresistant epilepsy in children as well as adults. Wilder, md, at mayo clinic,1,3 hippocrates established in the. The ketogenic diet has been used to treat children with epilepsy for almost a century.
The ketogenic diet for epilepsy learn about the diet, the medical conditions its. Ketogenic diet and diabetes pdf all articles about. Clinical care guidelines and strategies for managing the ketogenic diet in pediatric epilepsy jessica brown, rd, csp, cnsc ketogenic dietitian. The ketogenic diet is one treatment option for children or adults with epilepsy whose seizures are not controlled with aeds.
Clinical care guidelines and strategies for managing the. The cochrane library of clinical trials was searched using the. An introductory guide for the practical implementation of the. Although it has benefits as a medical treatment for certain groups of people, there is little evidence to recommend it as a longterm weight loss technique for healthy people. It also may help people with heart disease, certain brain.
Up to 70% of people with epilepsy could have their seizures controlled with antiepileptic drugs aeds. The ketogenic diet kd is used to treat refractory epilepsy, but the mechanisms underlying its neuroprotective effects remain unclear. Typical human diet fat protein carbohydrate the response of the body to fasting and starvation is a metabolic shift from the production and usage of glucose predominantly from dietary carbohydrates to ketones generated from fat stored in adipose tissue figure 3. If you still have questions after you have read this, please speak to one of the doctors, epilepsy.
The kd has a high fat content 90% and low protein and carbohydrate. In patients with pharmacoresistant epilepsy, a ketogenic diet has been observed to improve the quality of life and decreases seizure frequency in 30% of patients 25. The ketogenic diet meal plan for epilepsy involves the consumption of a specially tailored highfat, lowcarbohydrate diet which has been designed to help to control the seizures experienced by some people who suffer from epilepsy. A remembrance of life on the ketogenic diet 60 years later. Classic and modified ketogenic diets for treatment of epilepsy. Jan 14, 2020 the ketogenic diet for epilepsy kde is a special diet that has helped many children and some adults achieve better or even full control of their seizures. Find out what kinds of foods your child can eat if she takes up the ketogenic diet, and learn about the challenges and side effects of a meal plan that gets rid of seizures in some kids with epilepsy. Ketogenic diet has been used in patients with difficulttotreat epilepsy since 1921, with minor changes in recent years. Our regimen is a modification of the classic ketogenic diet, similar to the atkins diet. It is currently not recommended for newonset seizures because antiepileptic drugs aeds are easier to use and are effective in approx 7080% of patients.
Scientifically proven as treatment for intractable seizures in children, these ketonegenerating diets are increasingly also being used in adults. Every step of the ketogenic diet process must be managed by an. During the last two and onehalf years, the ketogenic, or high fat, diet has been given a trial in the treatment of epilepsy in childhood. It has been proposed as a dietary treatment that would produce similar benefits to fasting, which is already recorded in the hippocratic collection. Trying to put a child on the diet without medical guidance puts a child at risk of serious consequences. Jul 30, 2018 the ketogenic diet keto is a lowcarb, highfat diet that causes weight loss and provides numerous health benefits. Ketogenic diet meal plan for epilepsy matthews friends. Ketogenic diet is one of the oldest forms of medical treatment for epilepsy.
Please use one of the following formats to cite this article in your essay, paper or report. It makes the body burn fat for energy instead of glucose. The ketogenic diet offers the advantage of improved seizure. The diet may help to reduce the number or severity of seizures and may have other positive effects.
Further study assessing the efficacy of the ketogenic diet, and the cog nitive and longterm effects is ongoing. Guidelines for practical implementation of the ketogenic. If the medicines dont work, or cause bad side effects, doctors may. Prospective study of the modified atkins diet in combination with a ketogenic liquid. The ketogenic diet kd is a modality of treatment used since the 1920s as a treatment for intractable epilepsy. Th ey may suggest surgery to remove the part of the brain where the seizures begin. It is stricter than the modified atkins diet, requiring. The ketogenic diet is a high fat diet which appears to benefit some people with epilepsy, especially children. Jan 29, 2019 the ketogenic diet kd is a modality of treatment used since the 1920s as a treatment for intractable epilepsy.
It is usually used in children with seizures that do not respond to medications. The ketogenic diet is a recognised and proven therapy for epilepsy. The ketogenic diet kd, a wellestablished treatment for childhood epilepsy, is gradually gaining acceptance as a therapeutic modality for obesity and type 2 diabetes. The kd consists of a high fat, low carbohydrate and. Ketogenic diet for the treatment of refractory epilepsy in. The ketogenic diet keto is a lowcarb, highfat diet that causes weight loss and provides numerous health benefits. Ketogenic diet kd therapies are high fat, low carbohydrate diets designed to mimic a fasting state. It is prescribed by a physician and carefully monitored by a dietitian. A ketogenic or keto diet is a lowcarbohydrate, highfat diet. Ketogenic diet therapy for epilepsy epilepsy ontario. The ketogenic diet shows promise in both adult generalized and partial epilepsy. Few serious complications caused by the classic or modified ketogenic diet have been. Pdf management of epilepsy with ketogenic diet researchgate. The ketogenic diet is used in children with intractable epilepsy with good evidence, though it is used less commonly in neonates and there is less published evidence for use in this population.
Currently, it is used primarily to treat refractory childhood epilepsy 2,3. It is not a magic cure but one alternative to the various antiepileptic medications currently available. Ketogenic diet for the treatment of refractory epilepsy in children. The ketogenic diet kd has historically been used in the treatment of medically refractory epilepsy. It is a high fat, adequate protein, low carbohydrate diet used in difficult to control epilepsy. The ketogenic diet has been used for many years to treat children whose seizures are not responding to medication. The ketogenic diet kd is a highfat, lowcarbohydrate diet with adequate protein thats a nonpharmacologic treatment for refractory epilepsy. With no more glucose to provide energy, the childs body begins to burn stored fat. Guidelines for practical implementation of the ketogenic diet. Full text ketogenic dietary therapy for epilepsy and other disorders.
The ketogenic diet for children with epilepsy this leaflet has been given to you to help answer some of the questions you may have about the ketogenic diet as a treatment for epilepsy in children. Its a firstline treatment for a few specific epilepsy syndromes, such as epilepsy due to mutations in glut1 or pyruvate dehydrogenase deficiency. Evidence shows that kd and its variants are a good alternative. The major differentiating factor between them all is the amount of calories that come from protein, carbs, and fat. People use a ketogenic diet most often to lose weight, but it can help manage certain medical conditions, like epilepsy, too. The ketogenic diet is a diet with a strict ratio between fat and protein intake with very limited carbohydrates. The ketogenic diet is a highfat, lowcarbohydrate, lowprotein diet used in treatment of pediatric epilepsy since the 1920s 1. The ketogenic diet kd is thought to be an alternative way of treatment. Concerns about covid19 coronavirus and epilepsy epilepsy. It forces the childs body to burn fat around the clock by keeping calories low and making fat products the primary food that the child is getting. Optimal clinical management of children receiving the ketogenic diet. The ketogenic diet for intractable epilepsy in adults. Ketogenic diet treatment is a nonpharmacological therapy used worldwide, especially for children with epilepsy that is difficult to control.
1506 635 1426 772 965 170 185 881 1008 113 1370 664 1037 809 1362 889 582 923 228 937 1155 1072 401 1080 482 400 1298 102 1489 653 1169 1266 1473 1280 861 1147 1049 1221